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Asperger syndrome
Classification and external resources
Seated boy facing 3/4 away from camera, looking at a ball-and-stick model of a molecular structure. The model is made of colored magnets and steel balls.
People with Asperger syndrome often display intense interests, such as this boy’s fascination with molecular structure.
ICD10 F84.5
ICD9 299.80
OMIM 608638
Diseases DB 31268
Medline Plus 001549
eMedicine ped/147
MeSH F03.550.325.100

Asperger’s syndrome, also known as Asperger syndrome or Asperger disorder, is an autism spectrum disorder that is characterized by significant difficulties in social interaction, alongside restricted and repetitive patterns of behavior and interests. It differs from other autism spectrum disorders by its relative preservation of linguistic and cognitive development. Although not required for diagnosis, physical clumsiness and atypical use of language are frequently reported.[3][4]

Asperger syndrome is named after the Austrian pediatrician Hans Asperger who, in 1944, studied and described children in his practice who lacked nonverbal communication skills, demonstrated limited empathy with their peers, and were physically clumsy.[5] Fifty years later, it was standardized as a diagnosis, but many questions remain about aspects of the disorder.[6] For example, there is doubt about whether it is distinct from high-functioning autism (HFA);[7] partly because of this, its prevalence is not firmly established.[3] It has been proposed that the diagnosis of Asperger’s be eliminated, to be replaced by a diagnosis of autism spectrum disorder on a severity scale.[8]

The exact cause is unknown, although research supports the likelihood of a genetic basis; brain imaging techniques have not identified a clear common pathology.[3] There is no single treatment, and the effectiveness of particular interventions is supported by only limited data.[3] Intervention is aimed at improving symptoms and function. The mainstay of management is behavioral therapy, focusing on specific deficits to address poor communication skills, obsessive or repetitive routines, and physical clumsiness.[9] Most children improve as they mature to adulthood, but social and communication difficulties may persist.[6] Some researchers and people with Asperger’s have advocated a shift in attitudes toward the view that it is a difference, rather than a disability that must be treated or cured.[10][11]



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